The home side lost narrowly to the Winneba-based tertiary institution in a 20-18 contest. It was another second-rate display from the University of Ghana ladies who also lost grounds in their first game.
They lost their opening match on Sunday to the University of Cape Coast following a roller coaster display from their guest.
Elsewhere on Monday morning, Kwame Nkrumah University of Science and Technology ladies also accounted for the University of Cape Coast, winning 27-17.
Champions UEW continued their fine form in the boys division with 39-34 success over KNUST at the same venue.
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