The pair will be joined by fellow Captains Kemba Walker of Charlotte Hornets and Thabo Sefolosha of Atlanta Hawks on August 5 when the game takes place in Johannesburg, South Africa.
German international Nowitzki and Walker will captain Team World while Deng and Sefolosha will do same for Team Africa.
The NBA Game will be played to help raise funds for Charity following the 15th edition of Basketball Without Borders Program due to be held in Johannesburg.
Deng, who has played in the NBA since 2004 and earned two All-Star appearances, was born in South Sudan but represents Great Britain while Sefolosha’s father was born in South Africa.
The Atlanta Hawks Forward wrapped up his 11th year in the NBA and represents Switzerland in international competitions.
By Yaw Adjei-Mintah
@YawMintYM on Twitter