Braves of Customs, Tudu Magic and Ghana Police are the only teams yet to lose a game this season and all three teams play later today.
Police takes on homeside Reformers of Prisons in the opening game at 16:00 GMT in its third game this season; both teams competed in Division II last season.
Police has won two games in as many appearances and squares up against rival Prisons with a chance to extend the winning mark to three. Prisons have a win in three games to show for.
Defending league champions Braves face a tough challenge in the second and final game of the round against league leaders Tudu Magic.
Both sides are yet to lose a game this season as Magic has won all three games with Braves winning two games. At game’s end, one team’s winning streak is sure to end.
By Yaw Adjei-Mintah
@YawMintYM on Twitter