James, who created an instant powerhouse when he decided in July to join fellow All Stars Dwyane Wade and Chris Bosh in Miami, will play in Cleveland on December 2.
The two-time reigning NBA Most Valuable Player could be in for a rude homecoming as several people burned replica number 23 James jerseys in Cleveland moments after a televised announcement where he said he would play for Miami.
Bosh will also face his former team when Miami play the Toronto Raptors on February 16.
The Los Angeles Lakers will host the Boston Celtics on January 30 in a rematch of the 2010 NBA Finals, which the Lakers won in seven games. They will meet again in Boston on February 10.
Miami’s visit to the Celtics on the opening day of the 2010-11 NBA season was announced last week when the league unveiled portions of the schedule.