The two time champions beat Takoradi Technical University (TTU) 64-39 in the final game of the first day of competition in the quarterfinals.
The win follows a 49-29 win over Ghana Technology University College (GTUC) earlier in the day in Group A.
UG wrapped up a big performance with a 25 point win that had the host team take control of the game early on.
UG clinched a 33-15 first half lead but a 10-2 run early in the third quarter with Joel Kwame Opoku providing a highlight moment by stealing the ball and delivered a two handed slam.
His backcourt mate Emmanuel Wolff scored a three point shot from the left corner in front of his bench to cap the big run.
Takoradi Technical Guard Ibrahim Jafar was a big hit for his side but his efforts proved not enough as UG walked away with an emphatic win.
By Yaw Adjei-Mintah
@YawMintYM on Twitter